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pentobarbital will minimize the level or impact of ixabepilone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.pentobarbital decreases levels of elvitegravir/cobicistat/emtricitabine/tenofovir DF by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. May well produce loss of virologic response and f